Protein-protein or protein-ligand interactions are essential to almost every process in a cell, so understanding these interactions is crucial for understanding cell physiology in normal and disease states. It is also essential in drug development, since drugs can affect protein-protein or protein-ligand interaction. Protein interaction is mathematical representations of the physical contacts between proteins or protein-ligand in the cell. These contacts:
- are specific;
- occur between defined binding regions in the proteins or protein-ligand
